Synthetic membrane channels built out of DNA: Nanotech structures mimic nature's way of tunneling through cell walls

ScienceDaily (Nov. 20, 2012) ? As reported in the journal Science, physicists at the Technische Universitaet Muenchen (TUM) and the University of Michigan have shown that synthetic membrane channels can be constructed through "DNA nanotechnology." This technique employs DNA molecules as programmable building materials for custom-designed, self-assembling, nanometer-scale structures. The researchers present evidence that their nature-inspired nanostructures may also behave like biological ion channels. Their results could mark a step toward applications of synthetic membrane channels as molecular sensors, antimicrobial agents, and drivers of novel nanodevices.

Over the past three decades, researchers have advanced DNA nanotechnology from an intriguing idea to an emerging technology, with a toolbox of methods and a portfolio of nanometer-scale objects designed to demonstrate its potential. What's new here is the claim that DNA nanotech can be used to mimic one of the most widespread and important nanomachines in nature.

To wall off the insides of cells from the outside world, organisms in all three domains of life use the same kind of barrier: an impermeable membrane made from two layers of lipid molecules. Such membranes can also be found within cells, for example encapsulating the nucleus, and even surrounding many kinds of viruses. And to mediate between the different environments on either side of this universal barrier, nature provides a common type of passageway. Membrane channels are tube-like structures made of proteins, which pierce the barriers and regulate the two-way exchange of material and information between the inside and outside. Now researchers have demonstrated the first artificial membrane channel made entirely of DNA, and its characteristics suggest a number of potential applications. "If you want, for example, to inject something into a cell, you have to find a way to punch a hole into the cell membrane, and this device can do that, at least with model cell membranes," says TUM Prof. Hendrik Dietz, a fellow of the TUM Institute for Advanced Study.

In a shape inspired by a natural channel protein, the DNA-based membrane channel consists of a needle-like stem 42 nanometers long with an internal diameter of just two nanometers, partly sheathed by a barrel-shaped cap. A ring of cholesterol units around the edge of the cap helps the device "dock" to a lipid membrane while the stem sticks through it, forming a channel that appears to function like the real thing. TUM Professor Friedrich Simmel, co-coordinator of the Excellence Cluster Nanosystems Initiative Munich, explains: "We have not tested this yet with living cells, but experiments with lipid vesicles show that our synthetic device will bind to a bilayer lipid membrane in the right orientation, so that the stem both penetrates the membrane and holds at the surface, forming a pore."

Further experiments demonstrated that the resulting pores have electrical conductivity comparable to that of a natural cell wall with ion channels, suggesting that they might be able to act like voltage-controlled gates. The results also suggest that transmembrane current could be tuned by adjusting fine structural details of the synthetic channels. To test one potential application of the DNA nanotech devices, the researchers used them as "nanopores" for several different molecular sensing experiments. These confirmed that it is possible, by observing changes in the electrical characteristics, to record the passage of single molecules through synthetic membrane channels made from DNA. Because this approach allows both geometric and chemical tailoring of the membrane channels, it might offer advantages over two other families of molecular sensors, based on biological and solid-state nanopores respectively.

Other conceivable applications remain to be investigated. One notion is to imitate the action of viruses or phages, breaking through the cell walls of targeted bacteria to kill them. In gene therapy, synthetic membrane channels might be used as nano-needles to inject material into cells. Such channels could also be used in basic studies of cell metabolism. Another idea is to harness the so-called ion flux -- which in cell membranes moves material in and out through the channel -- to drive sophisticated nanodevices inspired by other natural mechanisms. "We might be able to mimic natural ion pumps, transport proteins, and rotary motors like the enzyme responsible for synthesizing ATP," says Dietz. "I love that idea. That's what keeps me running."

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Story Source:

The above story is reprinted from materials provided by Technische Universitaet Muenchen, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. M. Langecker, V. Arnaut, T. G. Martin, J. List, S. Renner, M. Mayer, H. Dietz, F. C. Simmel. Synthetic Lipid Membrane Channels Formed by Designed DNA Nanostructures. Science, 2012; 338 (6109): 932 DOI: 10.1126/science.1225624

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/fZz2BjNuoow/121120122008.htm

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Film Reviews: Spielberg's Lincoln and Twilight's Finale | New Raleigh

November, 20, 2012 , by Isaac Weeks

This week?s reviews basically boils down to a battle between good and evil, an attempt at cinematic art going against the last gasp of a billion dollar grossing series of crap. Yes, Steven Spielberg brings us Lincoln while Lucifer presents us with the finale of the Twilight saga. Who will emerge victorious?

Spielberg has been talking about doing a film based on the life of Abraham Lincoln since before the release of Jaws, it seems like. Originally planned as a starring vehicle for a post-Taken Liam Neeson, once a timetable was finally set Neeson was no longer available and Daniel Day Lewis signed up.

While a much better actor, Lewis? name at the top of the poster makes a bio-drama much less of a sure thing when it comes to box office receipts.
For serious film fans, the news of Lewis signing on makes Lincoln a must see, which is good news for Spielberg; after years of people joking about how schmaltzy his films can get, War Horse may have finally been the straw that broke the camel?s back for many audience members. Once you seemingly staff all of your films with a precocious tyke, a daddy issue of some sort, and John Williams hamming it up on the score, you have to send notice to cinephiles that is safe to drop 2-2/12 hours of their life on your newest extravaganza.

Lincoln opens with the president meeting with Union soldiers on the field of a battle to take place. He is first approached by two white soldiers who, while uniformed men in their twenties, give off the vibe of giggling schoolgirls. One begins to recite the Gettysburg Address to the man, before being called away. A black soldier standing nearby takes this moment to question the recent Emancipation Proclamation?s true value, when he and his men are still receiving subpar treatment when compared to soldiers of other colors. Before walking away, this soldier completes the Address in Lincoln?s presence, because this is a Spielberg movie.

The screenplay, credited to Tony Kushner (Munich, Angels in America), is adapted from the award-winning book Team of Rivals. In Rivals we were shown in detail a president who brilliantly managed a Cabinet filled with men who not only felt they were better equipped to hold Lincoln?s job, but many were from opposing political parties, which was unheard of at the time and is an ideal that is basically extinct today. As Secretary of State William Seward, David Strathairn is perhaps the epitome of this notion, as a man called on by Lincoln to do many things that he holds to be wrong, but as Lincoln?s closest confidante he knows he must do them for the sake of any possible end to slavery and the war.

Much will be made of Lewis? portrayal of Lincoln. Forgoing the traditional booming voice that has been the trademark of many impersonators, he goes for a more likely thin, high pitched tone that a man of his size would actually have. While it is a clich? now, Lewis truly disappears into the role. While his more cartoonish roles in There Will Be Blood and Gangs of New York may be what many think of when reciting their favorite roles of the man, this is Lewis? finest work to date, a performance that 99% of actors will fail to ever get near. As a man willing to lose it all to make sure that slavery never graces America?s shores again, Lewis manages to show us the humanity in a historical figure that we have come to believe was true to his core, with no room for grey.

While Spielberg somehow manages to fill almost every speaking role with a familiar character actor, in actuality making this one of the finest casts in film history, two actors stick out for their inability to yield to the material. Tommy Lee Jones manages to provide one of the worst performances of his career in the role of Thaddeus Stevens, a firebrand congressman who takes up the cause of ending slavery once and for all time and again. Jones basically plays himself in a wig, a figure that pops up from time to time to raise his voice and rally his men. Joseph Gordon-Levitt also appears as Robert Lincoln, the oldest son who shows up seemingly for the sole reason of casting a name young actor to hopefully bring in the young folks. Even more than Jones, Levitt appears out of his depth here, appearing to believe the only thing required for the role is a fake mustache and a deeper voice.

This isn?t a slag against either party, really; it?s just a question of how do you fail casting these two prime roles when even the smallest seemed to have talent lined up?

Lincoln is being released at the perfect time. If ever there were a film tailor-made for a Thanksgiving crowd, when families must decide harmoniously on what movie they will watch together, this is a crowd-pleaser for all ages.

I want you to think of the finest meal you?ve ever eaten. I mean the one meal that on your death bed you wouldn?t request, because you know there would be no way to replicate it and you would just die disappointed, as we all do anyway. Now picture that food 80% covered in shit. 20% of the meal is guaranteed to have not been touched even the slightest by the shit, so it?s safe to eat, and it will taste just as wonderful as you could ever hope for. Do you eat it anyway?

Welcome to the world of The Twilight Saga: Breaking Bad Part Two!

Before I touch on that 20%, let?s start by discussing the areas of fecal contamination. For those that need a quick primer: In TTS:BBPO, Bella Swan (seriously, why didn?t they just name her Rapunzel?) finally decided between the two monsters that were courting her and chose Edward, the vampire who had shown in the past that he had commitment issues and would leave her for weeks at a time. This made the Oompa Loompa with abs Jacob the werewolf (oh, I?m sorry, ?shape shifter?) very angry, until Ed sexed Bella to death and managed to get her pregnant, with Jake falling in love with the newborn. Two and a half hours saved; YOU?RE WELCOME!

Part Two opens with Bella walking around, all vampiry now and ready to lay it down on Ed. He points out, ?Hey, you have a baby btw, wanna see?? and she responds with, ?Meh.? They go hunting, where Bella attempts to grab a rock climber in a scene that wouldn?t make the cut on old episodes of?The Outer Limits due to the cheesy visual effects.

But the funny doesn?t stop there! After sucking on a mountain lion, Bella finally gets around to meeting her baby. It is during this scene that Jacob breaks the news that he has fallen for someone younger. Bella rightfully freaks out, with no one taking a second to point out that this whole series is based on a 100+ year old vampire falling for jailbait.

Word slowly trickles down that an evil vampire army is going to pay a visit to our friendly vampires? home, due to a misunderstanding that perhaps the new baby is actually a human baby turned vampire, which is shown to us to be a terrible thing to do for all involved. The Cullens? search the world for other friendly vampires that are willing to have their back in the upcoming fight, eventually amassing a 2nd graders idea of the world?s cultures; seriously, the participants from the Amazon are one step away from caricatures found in an old Tarzan film.

Bill Condon was once a director that many thought to have a bright future. We?re talking a man that brought out a great performance in Ian McKellen and made Brendan Fraser appear a competent actor with Gods and Monsters. The sad thing isn?t so much that he sold his soul for a chance to throw in with a potential moneymaker like Twilight, it?s that it is safe to assume that he sold out cheap. Seriously, the next person to get a huge paycheck from Summit Entertainment will be the first, so why not try to latch on with the next young-adult adaptation sure to flop; at least that way you may be able to put your own personal vision into a bit of the thing.

Acting wise, you get what you would expect. Kristen Stewart appears to enjoy making out with her boyfriend, Robert Pattinson is visibly happy that he is almost finished with this sideshow, and Taylor Lautner tries to pull his shirt off on cue without visibly nodding his head and asking, ?Line?? The only actor who seems to be having fun is Michael Sheen as head baddie Aro, but as with any dreck that Sheen signs on for in return for a bundle of cash, he manages to cross the line separating enthusiastic and hammy quite a few times before the end of the film.

But what about that 20% that is worth it, I hear no one ask. I will tread this subject carefully, as I honestly don?t want to ruin anything for anyone. It is safe to say that there is a battle scene, as that has been one of the main selling points to come across in ads for the film. However, somehow Condon was actually able to produce an action scene that is not only the most exciting of 2012 (beating even The Avengers in that regard), but also the most brilliantly written. From the nervous rocking going on in the chairs behind me, I knew that this scene wasn?t in the books, and by doing so the filmmakers had finally thrown something unexpected at the longtime fans of the franchise.

Honestly, if you are in a bind for time this week, I would say it?s safe to skip both of these releases. I?m not saying Lincoln isn?t worth watching; I?m merely suggesting perhaps wait until it is closer to Oscar pool time and then knock it out at the discount theater. As for Twilight?well, you already knew whether or not you were going to see that, didn?t you?

Read More

Entertainment , Other posts by Isaac Weeks.

Source: http://www.newraleigh.com/article/film-reviews-spielbergs-lincoln-and-twilights-finale/

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RTS and Squared Financial offer spot FX and precious metals trading

Singapore - RTS Realtime Systems and Squared Financial Services, a broker offering ECN-style trading, have announced that they have gone live with an algorithmic trading solution featuring spot foreign exchange (FX) and precious metals.

Squared Financial is a specialist provider of over-the-counter spot FX and metals markets, including gold bullion. With three algorithmic trading platforms, RTS offers connectivity across asset classes to more than 135 marketplaces.

Andy Woodhouse, Managing Director of Asia Pacific for RTS, said: "We expect that this initiative will be very attractive to those who want to expand into spot FX and metals either to hedge their currency exposure or to participate in the burgeoning gold and FX markets. By leveraging the Squared Financial expertise in the spot market and the robust RTS global trading solutions, client firms can very quickly expand their capabilities and improve their hedging experience."

Youssef Barakat, Head of Business Development for Squared Financial, said: "The Squared FIX 4.4 API (application programming interface) offers a gateway to our premium liquidity, and the comprehensive market data and full audit trail is ideally suited for traders who want to run automated strategies and multi-currency trading models. Through our exciting collaboration with RTS, we are very pleased to extend our offering to RTS clients. By applying careful liquidity management techniques, we anticipate a uniquely competitive solution for our clients where we hope to set a new benchmark in multi-asset trading and hedging."

As part of the collaboration, RTS developed an interface into the Squared Financial platform featuring market data on spot FX and precious metals. One of the first customers using this solution, Leonard Kok of Quantum Dynamics Management Pte Ltd., said: "I am currently using RTD Tango for algorithmic trading, and the inclusion of Squared Financial's spot FX and bullion prices into RTS will definitely open the door to new opportunities."

Woodhouse said that clients of Squared Financial or RTS can choose to adopt RTS' Tango OnDemand which features a packaged solution for algorithmic trading in a fully hosted environment. Barakat said that driven by customer demand, Squared Financial has plans to launch non-deliverable forwards (NDFs) and a series of other new instruments in the near future, include spot crude WTI, XAU/THB (Gold Ounces/Thai Baht) and USD/CNY (U.S. dollar/Chinese yuan).

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Source: http://www.automatedtrader.net/news/algorithmic-trading-news/141794/rts-and-squared-financial-offer-spot-fx-and-precious-metals--trading

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Cheap Furniture - Home Improvement

Furniture is one of the main parts of our homes. Lots of people choose to find the items of furniture for their price range. If you have the real idea about the furniture you have to buy in the market before you shop. We can get the best price for the modern furniture and traditional items. When the weather is cold you can look for modern furniture in outdoors. There are some designs of furniture that are available in the market. We are using the furniture for the kitchen, dining table and bedroom. Most of the furniture can be made by wood. The muebles baratos can be in demand of prices. There is some specially designed furniture for the nursery people. The retail furniture does not stock these furniture items in large numbers. We can get this furniture in affordable prices. In finding the cheapest furniture is not so hard.

Source: http://desiredhearts.com/home-care/cheap-furniture/

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How the major US stock indexes fared Monday

U.S. stocks shook off their post-election slump Monday, recording their biggest gain in more than two months. Investors appeared more optimistic about a deal to avoid a federal budget crisis and were encouraged by a pair of corporate earnings reports.

The Dow Jones industrial average closed up 207.65 points, or 1.7 percent, at 12,795.96.

The Standard & Poor's 500 index rose 27.01 points, or 2 percent, to 1,386.89.

The Nasdaq composite average gained 62.94, or 2.2 percent, to 2,916.07.

For the year:

The Dow is up 578.40 points, or 4.7 percent.

The S&P 500 is up 129.29 points, or 10.3 percent.

The Nasdaq is up 310.92 points, or 11.9 percent.

Source: http://news.yahoo.com/major-us-stock-indexes-fared-monday-211135337--finance.html

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Courteney Cox In A Bikini Vacationing In Miami (PHOTOS)

www.popsugar.com:

Courteney Cox touched down in Miami yesterday with her traveling companion, Coco Arquette. The pair was all smiles on the beach today, enjoying some fun with friends.

Read the whole story at www.popsugar.com

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Source: http://www.huffingtonpost.com/2012/11/19/courteney-cox-in-a-bikini-photos_n_2158020.html

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Anxiety linked to chest pain in children

ScienceDaily (Nov. 16, 2012) ? Psychological factors can have as much-or more-impact on pediatric chest pain as physical ones, a University of Georgia study found recently. UGA psychologists discovered pediatric patients diagnosed with noncardiac chest pain have higher levels of anxiety and depression than patients diagnosed with innocent heart murmurs-the noise of normal turbulent blood flow in a structurally normal heart.

The UGA research was done in collaboration with Children's Healthcare of Atlanta and Emory University.

"The fact that these psychological symptoms are higher in noncardiac chest pain patients suggests the psychological symptoms may be playing a role in the presentation of chest pain," said Jennifer Lee, a doctoral candidate in the UGA Franklin College of Arts and Sciences and the study's lead author.

The results of the study, which were published Nov. 5 in the Journal of Pediatric Psychology, show a statistically significant increase in anxiety and depression among patients who are later diagnosed with noncardiac chest pain when compared to patients diagnosed with innocent heart murmurs. Lee said it is not clear if the anxiety is a cause of the pain or if pain caused the anxiety in the sample group.

"The higher levels weren't so high as to cause a clinical diagnosis on their own, but when you contrast the two groups, there were statistically significant differences," said study co-author Ronald Blount, a psychology professor in the Franklin College.

The study included 129 patients ages 8 to 18. The group completed surveys prior to diagnosis. All patients were essentially in the same situation-sitting in a cardiology office awaiting their unknown medical diagnosis.

"We are highlighting that psychology has a part in these symptoms," Blount said, "and screening for psychological, as well as medical factors, is one implication we foresee coming from this investigation."

Chest pain can indicate serious medical conditions that require a doctor's evaluation. In adults, pain in the chest is often linked to a cardiac problem. In children, however, less than 2 percent of patients receive a cardiac diagnosis for their pain.

The Sibley Heart Center at Children's Healthcare of Atlanta is one of the largest pediatric heart centers in the world, seeing an average of 2,500 new patients with acute chest pain each year.

"We know up front that 99 percent of these patients will not have a heart complication at all. The trick is, it is not zero, and I cannot miss the one patient with heart disease because the consequences could be catastrophic," said Dr. Robert Campbell, chief of the Sibley Heart Center and division director of the department of pediatrics at the Emory University School of Medicine.

The study also observed that noncardiac chest pain patients have a higher level of functional disability-or the inability to participate in everyday activities like running across a football field or making it through a day without a nap. They also spent less time at school and were less involved in extra-curricular activities.

"These kids also report greater levels of physical symptoms with unclear causes, like joint pain, stomach aches, head aches," Lee said. "These symptoms are believed to be psychological manifestations of stress. Sometimes your brain doesn't tell you that you are stressed out, but your body does, so you will experience symptoms like these."

Pediatric patients with noncardiac chest pain also reported higher levels of anxiety sensitivity, a fear of experiencing physical symptoms and additionally fearing that those symptoms are related to a catastrophic health issue.

"Psychological functioning is heavily related to pain," Blount said. "Pain is a sensory experience, but your attention to one thing or another and your emotions can impact your experience of pain. And how debilitating the pain is for you can be determined by psychological and social factors. That is what we were interested in looking at."

Previous studies have shown reducing emotional symptoms can lead to better coping ability with pain, Lee said. "A goal with these patients would be to create a clearer, more comprehensive picture of what is going on and determine a better way to help these kids and adolescents."

Campbell said the UGA research helps him serve the majority of his patients who leave his office with a clean bill of health but unexplained chest pain.

"Most importantly what we've learned is that after a physical evaluation of the patient, we take the time to sit down with the family and find out what they are most worried about so we can address their psychological issues," Campbell said. "We've learned to pay attention and to be confident and reassuring. I need to make it clear to my patients and their parents that I'm not saying you are not having pain, but that the pain is not caused by your heart."

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Story Source:

The above story is reprinted from materials provided by University of Georgia. The original article was written by April Reese Sorrow.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. J. L. Lee, J. Gilleland, R. M. Campbell, G. L. Johnson, P. Simpson, K. J. Dooley, R. L. Blount. Internalizing Symptoms and Functional Disability in Children With Noncardiac Chest Pain and Innocent Heart Murmurs. Journal of Pediatric Psychology, 2012; DOI: 10.1093/jpepsy/jss111

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/mental_health/~3/xHm_7oBv1lI/121117184654.htm

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{fsc book club} Assignment 3 & 4 Recap: Soups, Baking, Frozen ...

We?re chugging right along with the FSC Book Club. We?ve tackled Soups & Baking Needs/Mixes and are now in the middle of the chapters on Frozen Food, Pasta and Sauce. We?re thrilled with how well it?s going! Folks are reading and cooking, adjusting recipes, asking questions and sharing what they?ve made. Our forum over on Goodreads has become a really nice little community. Drop by and say hello! Our adopted author Alana Chernila has been popping in the forums to answer questions, so take advantage of this access and ask away!

As a reminder, Alana will be visiting the From Scratch Club table at the Troy Farmers Market on Saturday, December 8. Stop by and visit us! Alana will also be teaching a class that afternoon (register here) and was interviewed for the latest episode of the From Scratch Club Podcast.

Here?s a round-up of a few of the Book Club check-ins from the past two assignments:

?Cornbread ? Aisle 6: I call this the ?best-evah cornbread? and a whole bunch of my blog followers have made it and agree!??

via?Kitchen Ninja?(read more?here!)

?Did the beans & am very excited to have them packaged up in two cup portions with 1 cup broth and frozen flat in the freezer. Used the extra in chili & it was quick and the beans were just the right texture.

I don?t know why I resist growing beans (actually, yes I do know why ? laziness) but I look forward to a pile o?beans in my freezer next summer. Or, maybe I?ll go for the pressure canner next year...?

via Auburn Meadow Farm

Book Clubbers share personal experiences and stories- just like in The Homemade Pantry. I?d like to second Tamara?s mention that after finishing the book, she feels like close friends with Alana! I feel like I know all of you book clubbers so well, even though I haven?t met most of you in ?real life?!

Meg made homemade pasta and then used it in homemade lasagna in honor of her sister?s adorable new baby girl!?via Meg of Small World Supper Club (read more here!)

Amy made the butternut squash soup and brought it to a dinner party! She also made chicken nuggets that are headed for the freezer for nights when her husband is home alone for dinner and a batch of macaroni and cheese.

?Ricotta mixed with some roasted garlic, topped with fresh spinach and roasted tomato sauce on homemade dough.??via Casey

An enthusiastic endorsement for Alana?s pie crust recipe from Susan!

?I made the lentil soup. This was my second taste of lentil soup ever. The recipe in the book turned out much better than the soup I had in a restaurant once.?
via Dawn

+++

And, just as we hoped, folks are keeping the discussion alive on past chapters too!?

A batch of homemade ricotta!?via Kitchen Cauldron

+++

The new FSC Book Club assignment will be posted on Goodreads tomorrow morning, Monday, November 19! We are embarking on breads, crackers and drinks! Those drinks include liqueur, so be sure to stop by??Don?t forget to follow the book club on?Twitter, tag us (@FSCBookClub) and use the #FSCBookClub hashtag when you post.

Source: http://fromscratchclub.com/2012/11/18/fsc-book-club-assignment-3-4-recap-soups-baking-frozen-foods-pasta-sauce/

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New Syrian ambassador to France is named

Munzer Makhous, newly named ambassador in France of Syrian opposition, is seen during a press conference, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. French President Francois Hollande and the new Syrian opposition leader have announced plans to install a new ambassador to represent Syria in France. The announcement came after talks Saturday at the presidential palace in Paris between Hollande and Moaz al-Khatib, head of the newly formed Syrian opposition coalition. France is the only Western country to have formally recognized the group as the representative of the Syrian people. (AP Photo/Thibault Camus)

Munzer Makhous, newly named ambassador in France of Syrian opposition, is seen during a press conference, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. French President Francois Hollande and the new Syrian opposition leader have announced plans to install a new ambassador to represent Syria in France. The announcement came after talks Saturday at the presidential palace in Paris between Hollande and Moaz al-Khatib, head of the newly formed Syrian opposition coalition. France is the only Western country to have formally recognized the group as the representative of the Syrian people. (AP Photo/Thibault Camus)

French President Francois Hollande, left, and head of the new Syrian National Coalition for Opposition and Revolutionary Forces Mouaz al-Khatib, right, give a press conference after a meeting, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. French President Francois Hollande and the new Syrian opposition leader have announced plans to install a new ambassador to represent Syria in France. The announcement came after talks Saturday at the presidential palace in Paris between Hollande and Moaz al-Khatib, head of the newly formed Syrian opposition coalition. France is the only Western country to have formally recognized the group as the representative of the Syrian people. (AP Photo/Thibault Camus)

French President Francois Hollande, left, welcomes head of the new Syrian National Coalition for Opposition and Revolutionary Forces Mouaz al-Khatib, prior to a meeting, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. France has taken a leading role among Western countries in supporting Syria's rebels. On Tuesday, it became the first Western nation to formally recognize Syria's newly formed opposition coalition as the sole legitimate representative of the Syrian people. (AP Photo/Thibault Camus)

French President Francois Hollande, second from left, head of the new Syrian National Coalition for Opposition and Revolutionary Forces Mouaz al-Khatib, second from right, Syrian opposition member Suheir Atassi, left, and French Foreign Minister Laurent Fabius, right, pose for photos, prior to a meeting, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. France has taken a leading role among Western countries in supporting Syria's rebels. On Tuesday, it became the first Western nation to formally recognize Syria's newly formed opposition coalition as the sole legitimate representative of the Syrian people. (AP Photo/Thibault Camus)

French President Francois Hollande, left, gestures as he welcomes head of the new Syrian National Coalition for Opposition and Revolutionary Forces Mouaz al-Khatib, right, prior to a meeting, at the Elysee Palace, in Paris, Saturday, Nov. 17, 2012. France has taken a leading role among Western countries in supporting Syria's rebels. On Tuesday, it became the first Western nation to formally recognize Syria's newly formed opposition coalition as the sole legitimate representative of the Syrian people. (AP Photo/Thibault Camus)

PARIS (AP) ? French President Francois Hollande and the new Syrian opposition leader announced plans Saturday to install an ambassador to represent Syria in France.

The surprise move came after talks at France's presidential palace between Hollande and Moaz al-Khatib, head of the newly formed Syrian opposition coalition. France recognized the coalition days after it was formed on Sunday ? and so far is the only Western country to do so.

Al-Khatib said the new envoy will be academic Mounzir Makhous, describing him as "one of the first to speak of liberty" in Syria. He holds four doctorate degrees and belongs to the Muslim Alawite sect of Islam, like Syrian President Bashar Assad, al-Khatib said. The new envoy was at the talks Saturday in Paris.

It was widely believed that France might agree to the appointment of an ambassador but not before a provisional Syrian government was formed. Al-Khatib suggested that a provisional government would come quickly.

"''We have no hidden agenda," al-Khatib said in a bid to reassure other nations.

More than 36,000 people have been killed since the Syrian uprising against Assad began in March 2011 and the new coalition is pressing for the means to defend Syrian civilians.

In other news, Turkish cameraman Cuneyt Unal who was captured by Syrian forces while covering fighting in the city of Aleppo in August has been released and will return to Turkey, a delegation who negotiated his freedom told Turkish media.

France has taken the lead in efforts to oust Assad's regime, and Hollande reiterated Saturday that the Syrian National Coalition for Opposition and Revolutionary Forces is for France the sole representative of the Syrian people and a future provisional government.

Hollande also confirmed that French Foreign Minister Laurent Fabius, who was also at Saturday's talks, will raise the issue of lifting the EU arms embargo against Syria at a meeting Monday in Brussels among European Union foreign ministers.

Fabius has suggested supplying defensive weapons so Syrian rebels can protect themselves from attacks by Assad's regime. Since May 2011, the EU has imposed a ban on the export of weapons and equipment to Syria that could be used for "internal repression. "

Fabius will also press EU partners to recognize the coalition, Hollande said.

Hollande said al-Khatib, a preacher-turned-activist, reassured him that the coalition he leads seeks unity of the Syrian people and France aim in moving quickly is to "assure its legitimacy and credibility."

The United States and other EU nations have said they prefer to wait and see whether the coalition truly represents the variety of people that make up Syria.

The coalition replaces the fractious Syrian National Council as the main opposition group ? also recognized first by France ? although that group makes up about a third of the 60-plus members of the new coalition.

"There will be an ambassador of Syria in France," Hollande, with al-Khatib at his side, told reporters after the meeting. He conceded later that a proper locale must still be found to house him. The current Syrian Embassy building doesn't belong to France, he noted.

Al-Khatib, with the coalition's two vice-presidents, Riad Seif and Suheir Atassi, met Friday in London with British Foreign Secretary William Hague and representatives of France, Germany, the United States and Turkey and Qatar. Lifting the arms embargo was discussed there as well.

The two journalists who had been held by Syrian forces ? Unal and reporter Bashar Fahmi ? a Jordanian citizen of Palestinian origin, had been working for the U.S.-based Alhurra TV.

Turkish opposition lawmaker Hasan Akgol said Saturday that Unal was in Damascus and would return to Turkey later in the day with a Turkish opposition party delegation, which held talks with Assad and other Syrian officials for his release. There was no information on Fahmi's whereabouts.

Unal told Turkey's NTV television that he and Fahmi were caught up in the fighting in Aleppo on Aug. 20 that killed Japanese journalist Mika Yamamoto. He said Fahmi was seriously injured in the fighting.

The cameraman carried his injured colleague into an apartment building where Aleppo residents tended to his wound. Unal left to seek more help but was captured by a group who later handed him over to Syrian government forces.

Unal said he has been locked up alone in a prison cell in Aleppo for the past three months living on "bread and potatoes," but was not ill-treated.

With emotion in his voice, Unal said he was happy to be released but was still "in shock."

___

Ganley can be reached on twitter.com at Elaine_Ganley.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2012-11-17-Syria/id-8e36d573bb354dae9d087c967d2f3deb

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RSV Season is Here & Preemie Awareness Day

Did you know that RSV is a seasonal disease like the flu? It is the most prevalent from November through March and is so contagious that most children catch it before the age of 2. It makes me wonder how many colds or sniffles my kids have had that may have been mild RSV and with a baby due at the end of the RSV season I know that I need to be particularly cautious during her early weeks of life. I have known infants who have had RSV, but did not realize how common mild cases are for children of all ages and that it was so contagious.

November 17^th is Preemie Awareness Day and as we enter RSV and flu season it is important that we are aware about how serious RSV can be on a premature newborn. Being pregnant with my third child and having multiple friends give birth to preemies it definitely caught my attention. What may manifest itself as a mild cold for a toddler or young child may cause severe or even deadly infections in a preemie or newborn?s lungs. It is impossible to keep our little ones from being exposed to germs especially if they have siblings in school, but there is a lot we can do to help prevent the spread of this disease.

Prevention is Key

RSV is very contagious and can be spread easily though touching, sneezing and coughing. Since there? s no treatment for RSV, parents should take the following preventive steps to help protect their child:

• Wash hands, toys, bedding, and play areas frequently
• Ensure you, your family, and any visitors in your home wash their hands or us hand sanitizer
• Avoid large crowds and people who are or have been sick
• Never let anyone smoke near your baby
• Speak with your child?s doctor if he or she may be at high risk for RSV, as a preventive therapy may be available

As we prepare to take a journey overseas to visit my family for a few weeks, we will be exposed to a lot of people and new germs so I need to be particularly cautious and be sure to keep our hands clean. The last thing I want is to be traveling with sick kids! I like to keep a small spray bottle of CleanWell Hand Sanitizer in my purse for traveling and when we are out of the house, because it is compact, alcohol free and lasts a long time. It is kid safe for your toddlers and young children and the Orange Vanilla scent makes me feel happy.

With the weather getting colder and holiday gatherings just a few days and weeks ahead, let us all be a little more cautious. Visiting a friend or family?s new baby over the holidays? Make sure to wash your hands and have your children wash their hands before visiting with them, even if you do not think you have any germs to spread. I know that this is usually a no-brainer when visiting a friend or family member and their new bundle at the hospital, but I know I am guilty of getting a little lax as infants get older or when in other social settings. The more efforts we make to keep from acquiring or spreading germs the better for everyone.

I wrote this review while participating in a campaign for Mom Central Consulting on behalf of MedImmune and I received a promotional item to thank me for my participation.

Source: http://www.theclothdiaperreport.com/2012/11/rsv-season-is-here-preemie-awareness-day-is-november-17th.html

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Wall Street inches up on China, but U.S. data weighs

NEW YORK (Reuters) - U.S. stocks rose modestly on Thursday, snapping a five-day losing streak, in the wake of weak data reflecting sluggish economic growth.

The advance came on hopes the Chinese government would take steps to bolster the country's slowing growth, and as U.S. jobless claims fell a lot more than expected in the latest week. Cyclical sectors like energy and financials, which are tied to the pace of growth, rallied.

Jobless claims dropped by 23,000 to 359,000, significantly more than the 4,000 drop that had been expected.

Still, the final read on second-quarter gross domestic product showed growth of 1.3 percent, weaker than an expected 1.7 percent. At the same time, August durable goods tumbled 13.2 percent, much more than the 5 percent drop expected.

"You put it all together, a lot of this is backward looking data, some of this is more forward looking. It's certainly a negative but not a disaster," said Tim Ghriskey, chief investment officer of Solaris Group in Bedford Hills, New York.

Pending home sales, released at 10:00 a.m. ET, fell 2.6 percent in August, compared with expectations for flat growth. The news follows Wednesday's report on new home sales, which were also weaker than expected. Equities were not impacted by the data.

The Dow Jones industrial average <.dji> was up 41.97 points, or 0.31 percent, at 13,455.48. The Standard & Poor's 500 Index <.spx> was up 4.67 points, or 0.33 percent, at 1,437.99. The Nasdaq Composite Index <.ixic> was up 6.92 points, or 0.22 percent, at 3,100.62.

In China, stocks rebounded from multi-year lows on speculation the China Securities Regulatory Commission would announce steps to support beleaguered domestic markets which could include changes to the initial public offering market. Traders said China's central bank fed $57.9 billion into money markets this week, the largest weekly injection in history.

China's securities regulator will hold a regular meeting on Thursday, but reforming the system for initial public offers is not on the agenda, a regulatory source told Reuters.

The news on possible steps by China lifted energy shares <.gspe> 0.8 percent and financials <.gspf> 0.7 percent on expectations the measures would boost U.S. demand and growth. Among the most active, Bank of America Corp rose 2.5 percent to $9.04 and Consol Energy added 3.4 percent to $30.30.

Also helping financials was Discover Financial Services , which rose 2.9 percent to $38.10 after reporting third-quarter earnings that beat expectations.

The world economy has been relying on China's growth to offset weakness in the United States and Europe. While the U.S. has shown signs of recovery and the Federal Reserve recently announced measures to support markets, slowing growth in China has been a concern, especially with Europe's debt crisis still in focus.

Spain is set to announce economic reforms and a 2013 budget on Thursday. The tension in Europe, underlined by anti-austerity measures in Madrid and Athens, contributed to the S&P's 1.9 percent drop over the past five days. Analysts said investors may look for U.S. stocks offering value after the recent declines.

Hewlett-Packard Co fell 1.1 percent to $16.93 after Jefferies downgraded the Dow component to "underperform," expecting continued problems in its personal computer segment.

Tempur-Pedic International Inc agreed to buy rival mattress maker Sealy Corp for about $242 million and assume about $750 million in debt. Tempur shares surged 17 percent to $31.41 while Sealy rose 4.7 percent to $2.24.

The S&P 500 is up 5.2 percent so far for the third quarter and 1.9 percent for September, historically a weak month for equities. Gains were largely tied to economy-boosting actions taken by the U.S. Federal Reserve and European Central Bank.

(Additional reporting by Chuck Mikolajczak; Editing by Bernadette Baum)

Source: http://news.yahoo.com/stock-index-futures-signal-higher-wall-street-open-084714680--finance.html

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Types of Home Inspections | Improvement Home

Your house is a special place. A place where you live and raise a family, but how much do you really know about your house? Knowing that your home is safe and sound is one of the most important things when you are trying to sell a house or just enjoy it's shelter. Home inspections give you the assurance that your home is a safe and sound place. There are many types of home inspections to consider when making a move; lets take a look at a few.

One type of inspection for your house is a pre-listing inspection. When you are planning to sell your home, you need to be able to identify and repair problem areas. An inspection before you place your home on the market can help you price your home to sell quickly.

Another type of inspection to look into is new construction progress inspection. When you are purchasing a new home that is currently under construction, it is advisable to have some things checked out to ensure your future home is going to be one you can enjoy for a long time. One thing I recommend you have performed is a foundation inspection. As soon as the foundation has been completed it should be professionally inspected to avoid any complications in the future.

Types of Home Inspections

A pre-purchase inspection is another type of home inspection that might help you in finding your new place to live. This is very important in making sure that you are getting what you are paying for in your new home.

The last type of inspection that I will mention is the one-year warranty inspection. Most homes come with a 12-month builder warranty. You can protect your investment by checking out the integrity of your home before that 12 month window is up.

Whether you are getting into a new home or moving out of your own, home inspections are the smart choice for you and your wallet.

Types of Home Inspections

Home Inspections Raleigh

Home Inspection Service

Source: http://improvement-home.blogspot.com/2012/09/types-of-home-inspections.html

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S&#39;pore green building movement takes to the streets | Eco-Business ...

The green building industry needs green attitudes from occupants to be effective. Image: SIEW.

Green buildings may have risen in popularity in Singapore in the past few years, but such buildings are ?green? only if their users are too.

This is why the local green building movement is moving beyond physical walls to reach out to the man in the street, Singapore Green Building Council (SGBC) president Tai Lee Siang told Eco-Business in a recent interview.

Strong government leadership here has enabled building owners to adopt newfangled green technology to make their buildings more efficient. ?But the industry is mindful that if the people who occupy them do not have a ?green attitude? to conserving energy and resources, such buildings will not function well,? he said.

The SGBC, an industry association with more than 300 members, is thus focusing its efforts to include engaging the wider community, so that ?green lifestyles can complement green buildings to achieve greater results?, he said.

For example, SGBC is collaborating with technology giant IBM and the Ministry of Education on ?Project Green Insights?, which will raise awareness of energy efficiency with schools in Singapore. Education is important, said Mr Tai, as green attitudes are best adopted from a young age and the youth will become the future generation of building users.

SGBC?s industry members, such as property developers Lend Lease, are also developing green leases where tenants have to agree to certain environmental targets when they lease a retail space.

This focus on the community will be the main theme at this year?s upcoming International Green Building Conference (IGBC), organized by SGBC, which will feature activities that reach out to tenants, consumers and the youth.

To be held at the Sands Expo and Convention Centre from 10 to 12 October, the conference will convene more than 50 international experts from 25 countries to speak on green buildings and sustainable lifestyles.

National building regulator, the Building and Construction Authority (BCA), is also set to unveil new Green Mark schemes for big users of energy such as supermarkets, retailers and data centres at the conference.

The Green Mark is a system developed by the BCA to rate buildings on their environmental performance. Singapore currently has more than 1,200 Green Mark buildings.

Director of BCA?s technology development group, Mr Tan Tian Chong noted in statement that since its launch in 2005, the Green Mark scheme has ?provided a meaningful differentiation of buildings in the real estate market.?

?Indeed, a Green Mark building is internationally recognized as having best practices in environmental design and performance. This can have positive value-add for building owners as well as end-users as they will be living and working in energy-efficient, greener and healthier environments. We will extend the Green Mark scheme to new frontiers to make Singapore an even greener and healthier place,? he said.

BCA also plans to introduce a web-based carbon calculator that will help building professionals determine the footprint of major construction materials and energy used in buildings.

To ensure that the industry is held to high standards, the SGBC will announce at the conference a new Green Services Certification Scheme, which will cover related sectors such as architectural design, mechanical and electrical services, energy management and consultancy, and contractors.

It is an extension of an existing Green Building Product Certification, launched in 2010, which certifies green building products. SGBC has certified a total of 144 green products to date.

Mr Tai noted that products are only one aspect of what makes a building green. Service providers, who help create such buildings, are also important. ?So the new scheme will create a certain benchmark? on which these providers can be certified,? he said.

Some 10,000 people are expected to attend October?s conference. It will be held together with Bex Asia 2012, an annual regional building expo focusing on eco-friendly products and solutions. Both events are part of the annual Singapore Green Building Week.

Some notable figures due to speak include Professor Jacqueline Cramer, Director of Utrecht Sustainability Institute and former Minister of Housing, Social Planning and the Environment of the Netherlands, Ms Jane Henley, chief executive of the World Green Building Council and the founder of Earth Hour, Mr Andy Ridley.

To register for the upcoming International Green Building Conference 2012, click here.

Source: http://www.eco-business.com/features/spore-green-building-movement-takes-to-the-streets/

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Anderson Cooper to Teresa Giudice: Grow Up!

Source: http://www.thehollywoodgossip.com/2012/09/anderson-cooper-to-teresa-giudice-grow-up/

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Police chief resigns, NM force has gone to the dog

VAUGHN, N.M. (AP) ? The police chief of the small eastern New Mexico town of Vaughn resigned Wednesday, leaving the town with just one certified member on its police force ? a drug-sniffing dog named Nikka.

Dave Romero, attorney for the town, said Wednesday that police Chief Ernest "Chris" Armijo decided to step down after news stories reported that he wasn't allowed to carry a gun because of his criminal background.

"He decided the attention was distracting," Romero said.

State officials said Armijo couldn't carry a gun since acknowledging that he owed tens of thousands of dollars in delinquent child support payments in Texas. Armijo also faces new felony charges after being accused of selling a town-owned rifle and pocketing the cash.

Romero said Armijo is working to clear up the latest case. He said Armijo has not ruled out seeking the police chief's position again if his case is resolved and the position is open.

According to records, the only qualified member of the Vaughn Police Department is Nikka, a drug-sniffing dog. Vaughn's other officer isn't certified and pleaded guilty to charges of assault and battery last year. Noncertified officers can't make arrests and can't carry firearms.

But Romero said not having an officer qualified to carry a gun didn't put Vaughn at risk. "England doesn't allow police officers to carry guns," he said. "Sometime the strongest weapon in law enforcement is communication."

Vaughn, a town of about 450 located 104 miles east of Albuquerque, is a quiet town that is an overnight stop for railroad workers. And while residents say there is no crime problem, the town is set deep in what U.S. Homeland Security Investigations officials say is an isolated region of the state popular with drug traffickers. Officials say the desolate roads in Guadalupe County make it hard for authorities to catch smugglers moving drugs from Mexico.

Guadalupe County Sheriff Michael Lucero said since news about the police chief's record became public his department has helped patrol Vaughn. But he said those efforts have put a slight strain on his already short-staffed department.

"I visit the town at least once a month," said Lucero. "The important thing is to keep a presence so residents know we're there to help if we're needed."

Romero said town officials are considering whether to hire another police chief or keep the department staffed with just one officer. He said it's unclear whether the town will keep the police dog, which had been in Armijo's care.

When approached by a reporter from The Associated Press at his Vaughn home, Armijo said he had no comment, and he declined to grant access to the canine for photographs or video.

The dog's kennel could be seen in Armijo's backyard, and a police truck marked "K-9" was parked in his driveway.

At Penny's Diner, residents said they were embarrassed by the attention the episode has put on the small town.

"There's just a whole lot of nothing going on here," said cook Joyce Tabor. "We have very little crime. It's quiet. So this really doesn't matter."

___

Follow Russell Contreras on Twitter at http://twitter.com/russcontreras

Source: http://news.yahoo.com/police-chief-resigns-nm-force-gone-dog-200452443.html

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Mozilla And The National Science Foundation Challenge Developers To Build ?Apps From The Future?

In June, Mozilla and the National Science Foundation (NSF) announced the Mozilla Ignite challenge. During the first phase of this $500,000 challenge, the two organizations invited anybody to submit ideas for applications that could make use of ultra-fast, next-generation networks. These ideas had to be related to education, healthcare, public safety, clean energy, transportation, workforce development, and advanced manufacturing. Today, Mozilla and the NSF announced the eight winning ideas and launched the second phase of the program, which focuses on putting these ideas into reality.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/D87KQ7nQyK4/

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The Popinator

You’re on the couch watching a movie and you need a snack but can’t be bothered getting off the couch. If you’ve got the Popinator?from Popcorn Indiana?then you can snack without moving or even having to dig your hands into a bowl or bag . By saying the word “Pop” , the kernel cannon will [...]

Source: http://the-gadgeteer.com/2012/09/25/the-popinator/

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Foursquare's 'Always On' feature tracks your VIPs near or far, Android app regains nearby check-in filter

If you have an urge to always know what your close friends and family members are up to, then Foursquare has the remedy. The popular social network has announced the availability of its new "Always On" option which allows you to receive continuous check-ins from a selected list of people -- even if you have notifications disabled. This slick new feature gives you the flexibility to create a list of VIPs that you'd like to keep tabs on opposed to receiving a play by play of everyone else's weekend excursion. For now, the toggle can only be found on Foursquare's website, but we wouldn't be surprised if this toggle headed to the company's cadre of apps in the near future. The Android app specifically just received a new update that brings back the nearby friends check-in filter users lost in the upgrade to 5.0 (iOS and BlackBerry saw it return in August) plus a "social history" that shows if your friends have visited a location and how many times, as well as a redesigned me card.

Filed under: Cellphones, GPS, Mobile

Foursquare's 'Always On' feature tracks your VIPs near or far, Android app regains nearby check-in filter originally appeared on Engadget on Wed, 26 Sep 2012 04:53:00 EDT. Please see our terms for use of feeds.

Permalink TechCrunch  |  Foursquare, Google Play  | Email this | Comments

Source: http://www.engadget.com/2012/09/26/foursquare-always-on-feature-now-available/

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Bill Clinton, still lying after all these years (Powerlineblog)

Share With Friends: | | Politics - Top Stories News, RSS Feeds and Widgets via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/250770179?client_source=feed&format=rss

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Statement from White House Drug Policy Director Kerlikowske on ...

Washington, D.C.--(ENEWSPF)--September 24, 2012. ?Today, Gil Kerlikowske, Director of National Drug Control Policy (ONDCP) released the following statement in response to survey data from the Department of Health and Human Services? (HHS) Substance Abuse and Mental Health Services Administration (SAMHSA) showing significant declines in the non-medical use of prescription drugs:

?These results are encouraging, but we cannot afford to take our eyes off the ball.? The abuse of painkillers in America continues to take too many lives, tear apart too many families, and place too many burdens on communities across the nation.?? According to the Centers for Disease Control and Prevention, prescription drug abuse remains an epidemic.?

The good news is that today?s findings prove yet again that we are not powerless against the problem of substance abuse in America.?Since day one, the Obama Administration has pursued a bipartisan and holistic approach to this challenge.?I am heartened by this progress because it shows that our prescription drug abuse action plan is working to make America healthier and safer. We still have more work to do, but we remain steadfast in our commitment to reversing this epidemic through a balanced approach.?

According to new data from the National Survey on Drug Use and Health (NSDUH), the number of young adults (people aged 18 to 25) who used prescription drugs for non-medical purposes in the past month declined 14 percent -- from 2 million in 2010 to 1.7 million in 2011. This decline has driven an overall 12 percent decline in the number of Americans abusing prescription drugs.??

To address the problem of prescription drug abuse, the Administration has released Epidemic: Responding to America's Prescription Drug Abuse Crisis. A national framework for reducing prescription drug diversion and abuse, the plan supports the expansion of state-based prescription drug monitoring programs, more convenient and environmentally responsible disposal methods to remove unused medications from the home, education for patients and healthcare providers, and reducing the prevalence of pill mills and doctor shopping through enforcement efforts.

The number of The National Survey on Drug Use and Health is a scientifically conducted annual survey of approximately 70,000 people throughout the country, aged 12 and older.? Because of its statistical power, it is the nation?s premier source of statistical information on the scope and nature of many substance abuse and mental health issues affecting the nation. The complete survey findings are available on the SAMHSA web site at: for more information about SAMHSA visit: http://www.samhsa.gov/

For more information on Administration drug policy and efforts to reduce drug use and its consequences visit www.WhiteHouse.gov/ONDCP

Source: whitehouse.gov/ondcp

Source: http://www.enewspf.com/latest-news/health-and-fitness/36797-statement-from-white-house-drug-policy-director-kerlikowske-on-hhs-report-showing-declines-in-prescription-drug-abuse.html

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google currents equivalent ?

as i'm fairly new to ubuntu, i was just wondering is there a sort of google currents type of program/ app for 12.04 it was the app i used the most on my tablet and on my phone

love you lots like jelly tots

chris

ps as i'm new expect lots of silly questions like this

Source: http://ubuntuforums.org/showthread.php?t=2061709&goto=newpost

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Getting Maximum Mobile Marketing Impact With Minimum Effort ...

Mobile marketing is one of the newest types of marketing, yet it actually incorporates elements of some of the oldest and well proven methods. Many of the same rules that apply to other kinds of marketing will apply to mobile marketing too. However, there are some noteworthy differences. This article presents some solid advice on getting the best from this brilliant advertising medium.

Make sure you market through all platforms your costumers might use. They should display correctly for mobile platforms like the iPhone, Android and Blackberry operating systems. A simple message that works on multiple devices is easier to use and implement than one that is custom to each device. Mobile marketing is reliant upon the KISS principle.

QR codes are a smart way to provide interactive content to your customers. QR codes allow you to easily share coupons, promotions, and discounts. With your cellphone the QR codes are easy to use and capture. These codes make it easy to quickly deliver information about your company to your customers.

TIP! Recruit friends and family to help you test every ad you send out to ensure it is working properly. You could even pay someone to test it for you if you want an unbiased opinion.

Mobile Marketing

Use mobile marketing in conjunction with all relevant online functions. Create material that will entice people to visit your website and enroll in your mobile marketing campaign. When you provide your reader room to comment and other ways that they can participate on your site, you will see your sales soar.

Take the time to conduct a usability test. You have to make sure that your customers will be able to view the content that you are sending them. Ask friends, family and coworkers to allow you to send them test messages and to check over them before you launch the campaign.

TIP! Location is the key to effective mobile marketing. Mobile marketing offers the unique chance to know where you are located.

Be aware of how the competition is using social media to market their products. You need to stand apart from the competition.

Maps and directions should be easy to use. It has become a standard trend for individuals to use their cell phone to find directions to where they are going. Make yourself accessible to them. Ensure that your maps can be easily read on the small screen of the average mobile device. Include a link that allows the customer to find your location through Google Maps.

Make sure that your content is relevant and purposeful. It?s easy to go overboard when entering the mobile marketing arena. Be sure your messages have a purpose. Each communication you have with your customer should be directed at promoting your business through the presentation of new information or opportunities for your customers or potential customers. If your content is responsive to your customers? desires, they will buy stuff from you.

TIP! Promote your new mobile marketing campaign as a means of gaining access to exclusive offers and special savings. Make sure that your other advertising efforts, online and in print, point out your mobile campaign?s existence.

Send a reminder to everyone on your mobile marketing list a few hours prior launching a big sale or event, provided that it is an acceptable hour to send texts. This will remind your customers that you have something big going on that they should check out.

Marketing Campaign

Before you go live with your mobile marketing campaign, be sure to test your advertisement first. Verify your message delivery system is functional before before beginning your marketing campaign. Additionally, try sending it to a test audience (e.g. co-workers) first to get feedback before you send it to your target audience.

TIP! When starting a mobile marketing campaign, make sure that it works correctly for the major mobile platforms. Search out information on all of the devices you wish to target your advertising towards, and take each into consideration when planning your campaign.

Social media is a wonderful way to advertise. You can encourage your customers to start talking up your company by rewarding them when they give you social network attention. Getting word of mouth working for you is an effective advertising method, even online and on phones.

You test your websites and related ads on various browsers. In the same way, you should also test mobile websites and related mobile ads on different mobile devices. Cell phones come in a variety of screen sizes, and they support a variety of different browsers, too. Your website and content might look different on each device. The least you could do is test your campaign on the most popular models.

Utilize the dedicated short code. Though there is a slight increase in price, it translates into a major increase in protection. You may also derive a bit of legal coverage from its use.

TIP! No customer base every really changes unless the entire market dictates the change, but remember that mobile customers can come or go due to influences outside of your market. New technology can lure your customers away.

Before your company decides on creating their own mobile app, make sure it?s something that is needed by your customers. If the app serves no discernible purpose or function, it is unlikely to garner attention from any of your prospective or existing customers.

Paying someone to create a mobile-optimized website for your mobile marketing campaign is usually a wise investment. It can be quite difficult to develop a mobile website that is attractive and appealing. Consider hiring outside qualified developers to ensure this goes smoothly.

Your mobile marketing campaign could use a mission statement, if for no other reason than to keep you focused on your goals. Maintaining your principles is key to you being successful in your business plans.

TIP! To achieve the highest success rate in your mobile marketing campaigns, only send the most valuable offers that you have available. This ensures that customers will be eager to see your offers rather than regarding them as a nuisance.

Mobile Marketing

Do not overdo your use of mobile marketing, or customers may get annoyed. If you?re just starting to utilize mobile marketing, be very methodical in the way that you use the information you have learned from this article. Gaining more customers and sales will result

Join me on Facebook:

www.facebook.com/maynaseric

Source: http://www.maynaseric.com/getting-maximum-mobile-marketing-impact-with-minimum-effort-2

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